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Clinical application of insulin pumps in the management of insulin dependent diabetes.

机译:胰岛素泵在胰岛素依赖型糖尿病治疗中的临床应用。

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摘要

Seven volunteers aged 12.0 to 17.9 years participated in a trial to compare conventional insulin treatment with continuous open loop (pump) insulin infusion. After 6 weeks of conventional treatment followed by 6 weeks of insulin pump treatment, 4 children chose to manage their diabetes permanently by means of the insulin pump. The mean blood glucose concentration (based on home blood glucose monitoring) while on conventional insulin treatment showed no appreciable change during the 6 weeks' treatment on an insulin pump. Compared with conventional treatment, however, the mean 24 hour blood glucose profiles of the patients on pump insulin showed less variation in the blood glucose throughout the day, together with an appreciably lower peak after breakfast. These improvements occurred despite increased dietary flexibility while on pump insulin. The insulin pump seems to be an acceptable form of treatment for some children and young adults with diabetes mellitus and gives near physiological control of blood glucose.
机译:七名年龄在12.0至17.9岁之间的志愿者参加了一项试验,以比较常规胰岛素治疗与连续开环(泵)胰岛素输注的情况。经过6周的常规治疗和6周的胰岛素泵治疗后,有4名儿童选择通过胰岛素泵永久性治疗糖尿病。在常规胰岛素治疗下的平均血糖浓度(基于家庭血糖监测)在用胰岛素泵治疗6周期间未显示明显变化。但是,与常规治疗相比,使用胰岛素泵的患者的平均24小时血糖曲线显示全天血糖变化较小,早餐后的峰值明显降低。尽管增加了胰岛素泵的饮食灵活性,但仍取得了这些改善。对于一些患有糖尿病的儿童和年轻人来说,胰岛素泵似乎是一种可以接受的治疗方式,并且可以对血糖进行近乎生理的控制。

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